Basic Information
ID: ALA3767212
Type: Binding
Description: Antagonist activity at human alpha7 receptor expressed in mouse Neuro2a cells assessed as inhibition of acetylcholine iodide-induced intracellular calcium level at 50 uM preincubated with PNU-120596 for 20 mins followed by acetylcholine iodide addition along with compound treatment measured every 2 sec for 3 mins by fluorescence microplate reader analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Neuro2a
Target: Neuronal acetylcholine receptor protein alpha-7 subunit(ALA2492)
Document: ALA3763033
Antagonist activity at human alpha7 receptor expressed in mouse Neuro2a cells assessed as inhibition of acetylcholine iodide-induced intracellular calcium level at 50 uM preincubated with PNU-120596 for 20 mins followed by acetylcholine iodide addition along with compound treatment measured every 2 sec for 3 mins by fluorescence microplate reader analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3767212
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 317.82 | 2.06 | 2.06 |