Basic Information
ID: ALA3767300
Type: Binding
Description: Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by microplate reader analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HeLa
Target: Histone deacetylase (HDAC1 and HDAC2)(ALA2111429)
Document: ALA3763112
Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by microplate reader analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3767300
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 308.38 | 0.53 | 0.53 |
| 265.31 | 1.73 | 1.73 |
| 293.37 | 2.35 | 2.35 |
| 321.42 | 2.85 | 2.85 |
| 349.48 | 3.98 | 3.98 |
| 301.29 | 2.01 | 2.01 |
| 307.39 | 2.65 | 2.65 |
| 293.37 | 2.35 | 2.35 |
| 301.29 | 2.01 | 2.01 |
| 334.20 | 3.04 | 3.04 |
| 325.37 | 1.75 | 1.75 |
| 313.33 | 1.88 | 1.88 |
| 313.79 | 2.69 | 2.69 |
| 315.32 | 1.68 | 1.68 |
| 348.23 | 2.71 | 2.71 |
| 315.32 | 1.68 | 1.68 |
| 339.39 | 1.42 | 1.42 |
| 315.32 | 1.68 | 1.68 |
| 307.39 | 2.02 | 2.02 |
| 307.39 | 2.02 | 2.02 |