Basic Information
ID: ALA3767536
Type: Functional
Description: Antiproliferative activity against human NCI-H1975 cells harboring EGFR L858R/T790M double mutant assessed as reduction in cell viability after 72 hrs by MTT assay
Organism: Homo sapiens
Cell type: NCI-H1975
Activity Charts
Bioactivity
Activity Types for Assay ALA3767536
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 446.91 | 4.28 | 4.28 |
| 571.72 | 5.18 | 5.18 |
| 585.75 | 5.49 | 5.49 |
| 571.72 | 5.18 | 5.18 |
| 606.17 | 5.84 | 5.84 |
| 596.73 | 5.05 | 5.05 |
| 546.67 | 5.12 | 5.12 |
| 546.67 | 5.58 | 5.58 |
| 571.72 | 5.64 | 5.64 |
| 560.70 | 5.89 | 5.89 |
| 560.70 | 5.89 | 5.89 |
| 576.69 | 5.59 | 5.59 |
| 571.68 | 5.45 | 5.45 |