Basic Information
ID: ALA3767622
Type: Binding
Description: Inverse agonist activity at GST tagged-human CAR-LBD assessed as reduction in fluorescein-PGC1 alpha coactivator recruitment after 1 hr by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3767622
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 344.85 | 5.38 | 5.38 |
| 352.87 | 5.43 | 5.43 |
| 367.45 | 3.63 | 3.63 |
| 409.53 | 4.75 | 4.75 |
| 423.56 | 5.14 | 5.14 |
| 339.40 | 2.98 | 2.98 |
| 381.48 | 3.97 | 3.97 |
| 422.53 | 3.27 | 3.27 |
| 395.50 | 4.36 | 4.36 |
| 395.50 | 4.36 | 4.36 |
| 367.45 | 3.58 | 3.58 |
| 480.61 | 3.41 | 3.41 |
| 276.46 | 4.78 | 4.78 |
| 409.49 | 3.35 | 3.35 |
| 395.50 | 4.41 | 4.41 |
| 423.51 | 3.74 | 3.74 |
| 409.49 | 3.35 | 3.35 |
| 423.56 | 5.14 | 5.14 |
| 423.56 | 5.14 | 5.14 |
| 393.49 | 4.11 | 4.11 |
| 407.51 | 4.50 | 4.50 |
| 463.62 | 6.06 | 6.06 |
| 419.53 | 4.65 | 4.65 |
| 419.44 | 2.94 | 2.94 |
| 389.46 | 4.52 | 4.52 |
| 390.44 | 3.92 | 3.92 |
| 409.53 | 4.80 | 4.80 |
| 407.51 | 4.50 | 4.50 |
| 396.49 | 4.83 | 4.83 |
| 393.53 | 4.53 | 4.53 |
| 409.53 | 4.75 | 4.75 |
| 423.56 | 5.14 | 5.14 |
| 394.52 | 3.93 | 3.93 |
| 408.55 | 4.32 | 4.32 |
| 422.57 | 4.71 | 4.71 |
| 422.57 | 4.67 | 4.67 |
| 430.57 | 3.06 | 3.06 |
| 405.50 | 4.23 | 4.23 |
| 437.58 | 5.53 | 5.53 |
| 421.54 | 4.89 | 4.89 |
| 403.48 | 4.91 | 4.91 |
| 382.46 | 4.44 | 4.44 |
| 396.49 | 4.83 | 4.83 |
| 410.51 | 5.22 | 5.22 |
| 424.54 | 5.47 | 5.47 |
| 394.47 | 4.59 | 4.59 |
| 408.50 | 4.98 | 4.98 |
| 422.53 | 5.37 | 5.37 |
| 436.55 | 5.76 | 5.76 |
| 451.61 | 5.92 | 5.92 |
| 435.57 | 5.28 | 5.28 |
| 410.51 | 5.22 | 5.22 |
| 417.51 | 5.30 | 5.30 |
| 401.47 | 4.66 | 4.66 |
| 415.49 | 5.05 | 5.05 |
| 429.52 | 5.44 | 5.44 |
| 443.55 | 5.83 | 5.83 |