Basic Information
ID: ALA3767676
Type: Binding
Description: Inhibition of full length human 11beta-HSD2 expressed in HEK293 cells using cortisone as substrate incubated for 2 hrs by HTRF assay in presence of NAD+
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3767676
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 470.60 | 3.27 | 3.27 |
| 400.52 | 3.81 | 3.81 |
| 349.43 | 3.79 | 3.79 |
| 385.49 | 3.34 | 3.34 |
| 533.66 | 3.55 | 3.55 |
| 362.54 | 6.44 | 6.44 |
| 380.52 | 4.26 | 4.26 |
| 432.59 | 5.60 | 5.60 |
| 436.71 | 6.81 | 6.81 |
| 353.49 | 5.43 | 5.43 |
| 369.56 | 5.90 | 5.90 |
| 369.55 | 5.30 | 5.30 |
| 369.55 | 4.68 | 4.68 |
| 395.59 | 5.22 | 5.22 |
| 359.42 | 4.09 | 4.09 |
| 343.49 | 3.91 | 3.91 |
| 426.97 | 5.91 | 5.91 |
| 394.54 | 5.12 | 5.12 |
| 412.51 | 2.94 | 2.94 |
| 464.59 | 4.28 | 4.28 |
| 468.71 | 5.49 | 5.49 |
| 385.49 | 4.11 | 4.11 |
| 401.55 | 4.58 | 4.58 |
| 220.31 | 2.49 | 2.49 |
| 192.26 | 1.85 | 1.85 |
| 254.33 | 2.99 | 2.99 |
| 220.36 | 3.70 | 3.70 |
| 348.60 | ||
| 234.29 | 2.42 | 2.42 |
| 298.38 | 3.05 | 3.05 |
| 234.29 | 2.58 | 2.58 |
| 336.55 | ||
| 248.37 | 3.53 | 3.53 |
| 266.38 | 2.91 | 2.91 |
| 320.39 | 2.60 | 2.60 |
| 233.31 | 1.98 | 1.98 |
| 236.35 | 2.67 | 2.67 |
| 234.29 | 2.25 | 2.25 |
| 222.33 | 2.71 | 2.71 |
| 236.31 | 1.70 | 1.70 |
| 364.60 | ||
| 252.35 | 1.88 | 1.88 |
| 254.37 | 1.86 | 1.86 |
| 254.37 | 1.86 | 1.86 |
| 254.37 | 1.86 | 1.86 |
| 466.86 | ||
| 264.36 | 3.14 | 3.14 |
| 262.39 | 4.12 | 4.12 |
| 324.42 | 2.47 | 2.47 |
| 324.42 | 2.90 | 2.90 |
| 322.45 | 3.89 | 3.89 |
| 336.43 | 3.07 | 3.07 |
| 254.37 | 1.96 | 1.96 |
| 254.37 | 1.96 | 1.96 |
| 254.37 | 1.96 | 1.96 |
| 238.37 | 2.99 | 2.99 |
| 256.39 | 1.94 | 1.94 |
| 256.39 | 1.94 | 1.94 |
| 228.29 | 2.01 | 2.01 |
| 260.33 | 1.40 | 1.40 |
| 244.29 | 1.22 | 1.22 |
| 242.27 | 2.10 | 2.10 |
| 274.32 | 1.25 | 1.25 |
| 276.33 | 1.33 | 1.33 |