Basic Information
ID: ALA3767772
Type: ADME
Description: Inhibition of CYP2C9 in human liver microsomes assessed as diclofenac alpha'-hydroxylation
Format: BAO_0000221
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 2C9(ALA3397)
Document: ALA3763146
Inhibition of CYP2C9 in human liver microsomes assessed as diclofenac alpha'-hydroxylation: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3767772
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 624.71 | 6.56 | 6.56 |
| 422.55 | 3.30 | 3.30 |
| 444.54 | 2.77 | 2.77 |
| 434.57 | 3.60 | 3.60 |
| 417.51 | 2.80 | 2.80 |
| 468.56 | 3.43 | 3.43 |
| 418.50 | 2.28 | 2.28 |
| 418.50 | 2.28 | 2.28 |