Basic Information
ID: ALA3767953
Type: Binding
Description: Inhibition of human MRP1 transfected in MDCK2 cells assessed as inhibition of calcein-AM efflux
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MDCK-II
Target: Multidrug resistance-associated protein 1(ALA3004)
Document: ALA3763047
Inhibition of human MRP1 transfected in MDCK2 cells assessed as inhibition of calcein-AM efflux: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3767953
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 537.08 | 6.48 | 6.48 |
| 646.74 | 6.37 | 6.37 |
| 379.46 | 2.94 | 2.94 |
| 441.54 | 3.52 | 3.52 |
| 459.50 | 4.36 | 4.36 |
| 454.53 | 4.33 | 4.33 |
| 395.42 | 3.03 | 3.03 |
| 425.44 | 3.04 | 3.04 |
| 439.47 | 3.08 | 3.08 |
| 380.44 | 3.13 | 3.13 |
| 416.42 | 3.41 | 3.41 |
| 394.47 | 3.17 | 3.17 |
| 410.47 | 3.14 | 3.14 |
| 411.41 | 3.05 | 3.05 |
| 425.44 | 3.04 | 3.04 |
| 438.48 | 2.92 | 2.92 |
| 405.45 | 3.00 | 3.00 |
| 425.44 | 3.04 | 3.04 |
| 458.54 | 2.54 | 2.54 |
| 448.44 | 4.15 | 4.15 |
| 480.51 | 4.74 | 4.74 |
| 512.51 | 3.43 | 3.43 |
| 395.46 | 2.71 | 2.71 |
| 437.50 | 3.09 | 3.09 |
| 304.35 | 1.56 | 1.56 |
| 439.42 | 2.68 | 2.68 |
| 422.44 | 2.67 | 2.67 |
| 385.42 | 3.48 | 3.48 |
| 348.40 | 1.94 | 1.94 |
| 467.48 | 2.72 | 2.72 |
| 453.45 | 2.68 | 2.68 |
| 439.42 | 2.37 | 2.37 |
| 439.42 | 2.37 | 2.37 |