Basic Information
ID: ALA3768327
Type: Binding
Description: Binding affinity to LRP6 in human SH-SY5Y cells assessed as DKK1/LRP6 interaction-mediated increase in beta-catenin level at 10 uM incubated for 1 hr using compound pre-treated DKK1 conditioned media by Western blot analysis
Organism: Homo sapiens
Cell type: SH-SY5Y
Activity Charts
Bioactivity
Activity Types for Assay ALA3768327
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 329.31 | 1.43 | 1.43 |
| 405.41 | 3.59 | 3.59 |
| 419.44 | 3.90 | 3.90 |
| 435.44 | 3.60 | 3.60 |
| 474.30 | 4.90 | 4.90 |
| 449.46 | 3.47 | 3.47 |
| 397.43 | 2.84 | 2.84 |
| 411.46 | 3.60 | 3.60 |
| 399.40 | 1.69 | 1.69 |
| 397.43 | 3.21 | 3.21 |
| 491.54 | 4.64 | 4.64 |