Basic Information
ID: ALA3768328
Type: Binding
Description: Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned media after 2 hrs by fluorescence microscopic analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3768328
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 336.73 | 1.76 | 1.76 |
| 329.31 | 1.43 | 1.43 |
| 405.41 | 3.59 | 3.59 |
| 419.44 | 3.90 | 3.90 |
| 435.44 | 3.60 | 3.60 |
| 474.30 | 4.90 | 4.90 |
| 449.46 | 3.47 | 3.47 |
| 397.43 | 2.84 | 2.84 |
| 411.46 | 3.60 | 3.60 |
| 399.40 | 1.69 | 1.69 |
| 397.43 | 3.21 | 3.21 |
| 491.54 | 4.64 | 4.64 |