Basic Information
ID: ALA3768330
Type: Binding
Description: Binding affinity to LRP6 in human SH-SY5Y cells assessed as inhibition of DKK1/LRP6 interaction-mediated tau phosphorylation at serine 396 at 10 uM incubated for 1 hr using compound pre-treated DKK1 conditioned media by Western blot analysis
Organism: Homo sapiens
Cell type: SH-SY5Y
Activity Charts
Bioactivity
Activity Types for Assay ALA3768330
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 329.31 | 1.43 | 1.43 |
| 474.30 | 4.90 | 4.90 |
| 397.43 | 2.84 | 2.84 |