Assay Report Card

Basic Information

ID: ALA3768597

Type: Binding

Description: Inhibition of ATM in human MCF7 cells assessed as inhibition of p53 phosphorylation at Ser15 residue preincubated for 30 mins followed cells exposed to 10 Gy irradiation measured after 1 hr by western blot analysis

Organism: Homo sapiens

Cell type: MCF7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
395.514.764.76
349.351.871.87
437.461.911.91
393.411.891.89
478.512.772.77