Basic Information
ID: ALA3772525
Type: Binding
Description: Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ATP addition measured after 60 mins by Z-LYTE assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Serine/threonine-protein kinase PAK 1(ALA4600)
Document: ALA3769359
Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ATP addition measured after 60 mins by Z-LYTE assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3772525
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 518.07 | 5.04 | 5.04 |
| 490.01 | 4.31 | 4.31 |
| 463.97 | 4.05 | 4.05 |
| 504.04 | 4.83 | 4.83 |
| 503.05 | 5.43 | 5.43 |
| 490.01 | 4.44 | 4.44 |
| 450.93 | 3.69 | 3.69 |
| 503.99 | 3.84 | 3.84 |
| 477.96 | 2.91 | 2.91 |
| 507.98 | 3.01 | 3.01 |
| 492.97 | 3.22 | 3.22 |
| 506.99 | 3.48 | 3.48 |
| 519.01 | 3.49 | 3.49 |
| 510.98 | 4.77 | 4.77 |