Basic Information
ID: ALA3772537
Type: Functional
Description: Antagonist activity at human C-C chemokine receptor type 2 expressed in THP-1 cells assessed as inhibition of CCL2-induced calcium flux preincubated for 10 mins followed by CCL2 addition by Fluo-4 dye based FLIPR assay
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA3772537
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 443.02 | 2.28 | 2.28 |
| 455.03 | 2.42 | 2.42 |
| 482.96 | 2.56 | 2.56 |
| 457.04 | 2.45 | 2.45 |
| 420.58 | 1.77 | 1.77 |
| 440.59 | 1.94 | 1.94 |
| 398.51 | 1.03 | 1.03 |
| 424.57 | 1.21 | 1.21 |
| 473.44 | 1.96 | 1.96 |
| 414.96 | 1.54 | 1.54 |
| 428.99 | 1.85 | 1.85 |
| 428.99 | 1.72 | 1.72 |