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Inhibition of human NAAA expressed in HEK293 cells preincubated for 10 mins followed by N-(4-methyl-2-oxo-chromen-7-yl)-hexadecanamide substrate addit...

Basic Information

ID: ALA3772811

Type: Binding

Description: Inhibition of human NAAA expressed in HEK293 cells preincubated for 10 mins followed by N-(4-methyl-2-oxo-chromen-7-yl)-hexadecanamide substrate addition for 50 mins by fluorescence assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HEK293

Target:  N-acylsphingosine-amidohydrolase(ALA4349)

Document:  ALA3769304

Inhibition of human NAAA expressed in HEK293 cells preincubated for 10 mins followed by N-(4-methyl-2-oxo-chromen-7-yl)-hexadecanamide substrate addition for 50 mins by fluorescence assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
228.291.181.18
268.361.961.96
242.321.571.57
276.341.621.62
296.332.082.08
254.331.571.57
282.382.352.35
270.330.810.81
270.330.950.95
270.330.810.81
304.342.212.21
268.361.961.96
254.331.571.57
262.311.231.23
290.361.801.80
292.331.241.24
330.312.252.25
263.300.630.63
260.291.311.31
260.291.311.31
302.372.462.46
302.372.462.46
302.372.462.46
288.352.072.07
234.250.720.72
248.280.970.97
262.311.361.36
276.341.751.75
276.341.711.71
274.321.291.29
260.290.900.90
316.403.023.02
304.351.311.31
318.372.122.12
278.311.201.20
264.240.140.14
300.220.730.73
297.311.471.47
287.281.071.07
268.361.961.96
282.382.352.35
282.382.352.35
282.382.352.35
282.382.352.35
296.412.742.74
296.412.742.74