Basic Information
ID: ALA3772811
Type: Binding
Description: Inhibition of human NAAA expressed in HEK293 cells preincubated for 10 mins followed by N-(4-methyl-2-oxo-chromen-7-yl)-hexadecanamide substrate addition for 50 mins by fluorescence assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3772811
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 228.29 | 1.18 | 1.18 |
| 268.36 | 1.96 | 1.96 |
| 242.32 | 1.57 | 1.57 |
| 276.34 | 1.62 | 1.62 |
| 296.33 | 2.08 | 2.08 |
| 254.33 | 1.57 | 1.57 |
| 282.38 | 2.35 | 2.35 |
| 270.33 | 0.81 | 0.81 |
| 270.33 | 0.95 | 0.95 |
| 270.33 | 0.81 | 0.81 |
| 304.34 | 2.21 | 2.21 |
| 268.36 | 1.96 | 1.96 |
| 254.33 | 1.57 | 1.57 |
| 262.31 | 1.23 | 1.23 |
| 290.36 | 1.80 | 1.80 |
| 292.33 | 1.24 | 1.24 |
| 330.31 | 2.25 | 2.25 |
| 263.30 | 0.63 | 0.63 |
| 260.29 | 1.31 | 1.31 |
| 260.29 | 1.31 | 1.31 |
| 302.37 | 2.46 | 2.46 |
| 302.37 | 2.46 | 2.46 |
| 302.37 | 2.46 | 2.46 |
| 288.35 | 2.07 | 2.07 |
| 234.25 | 0.72 | 0.72 |
| 248.28 | 0.97 | 0.97 |
| 262.31 | 1.36 | 1.36 |
| 276.34 | 1.75 | 1.75 |
| 276.34 | 1.71 | 1.71 |
| 274.32 | 1.29 | 1.29 |
| 260.29 | 0.90 | 0.90 |
| 316.40 | 3.02 | 3.02 |
| 304.35 | 1.31 | 1.31 |
| 318.37 | 2.12 | 2.12 |
| 278.31 | 1.20 | 1.20 |
| 264.24 | 0.14 | 0.14 |
| 300.22 | 0.73 | 0.73 |
| 297.31 | 1.47 | 1.47 |
| 287.28 | 1.07 | 1.07 |
| 268.36 | 1.96 | 1.96 |
| 282.38 | 2.35 | 2.35 |
| 282.38 | 2.35 | 2.35 |
| 282.38 | 2.35 | 2.35 |
| 282.38 | 2.35 | 2.35 |
| 296.41 | 2.74 | 2.74 |
| 296.41 | 2.74 | 2.74 |