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ID: ALA3772811
Type: Binding
Description: Inhibition of human NAAA expressed in HEK293 cells preincubated for 10 mins followed by N-(4-methyl-2-oxo-chromen-7-yl)-hexadecanamide substrate addition for 50 mins by fluorescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: N-acylsphingosine-amidohydrolase(ALA4349)
Document: ALA3769304
Inhibition of human NAAA expressed in HEK293 cells preincubated for 10 mins followed by N-(4-methyl-2-oxo-chromen-7-yl)-hexadecanamide substrate addition for 50 mins by fluorescence assay: 1
Bioactivity
Activity Types for Assay ALA3772811
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
228.29 | 1.18 | 1.18 |
268.36 | 1.96 | 1.96 |
242.32 | 1.57 | 1.57 |
276.34 | 1.62 | 1.62 |
296.33 | 2.08 | 2.08 |
254.33 | 1.57 | 1.57 |
282.38 | 2.35 | 2.35 |
270.33 | 0.81 | 0.81 |
270.33 | 0.95 | 0.95 |
270.33 | 0.81 | 0.81 |
304.34 | 2.21 | 2.21 |
268.36 | 1.96 | 1.96 |
254.33 | 1.57 | 1.57 |
262.31 | 1.23 | 1.23 |
290.36 | 1.80 | 1.80 |
292.33 | 1.24 | 1.24 |
330.31 | 2.25 | 2.25 |
263.30 | 0.63 | 0.63 |
260.29 | 1.31 | 1.31 |
260.29 | 1.31 | 1.31 |
302.37 | 2.46 | 2.46 |
302.37 | 2.46 | 2.46 |
302.37 | 2.46 | 2.46 |
288.35 | 2.07 | 2.07 |
234.25 | 0.72 | 0.72 |
248.28 | 0.97 | 0.97 |
262.31 | 1.36 | 1.36 |
276.34 | 1.75 | 1.75 |
276.34 | 1.71 | 1.71 |
274.32 | 1.29 | 1.29 |
260.29 | 0.90 | 0.90 |
316.40 | 3.02 | 3.02 |
304.35 | 1.31 | 1.31 |
318.37 | 2.12 | 2.12 |
278.31 | 1.20 | 1.20 |
264.24 | 0.14 | 0.14 |
300.22 | 0.73 | 0.73 |
297.31 | 1.47 | 1.47 |
287.28 | 1.07 | 1.07 |
268.36 | 1.96 | 1.96 |
282.38 | 2.35 | 2.35 |
282.38 | 2.35 | 2.35 |
282.38 | 2.35 | 2.35 |
282.38 | 2.35 | 2.35 |
296.41 | 2.74 | 2.74 |
296.41 | 2.74 | 2.74 |