Competitive inhibition of BRD4 in PMA /ionomycin activated human Jurkat cell lysate in presence of (S)-4-{3'-Cyano-4'-[3-(3-{2-[5-((3aR,6S,6aS)-2-oxo-...

Basic Information

ID: ALA3772988

Type: Binding

Description: Competitive inhibition of BRD4 in PMA /ionomycin activated human Jurkat cell lysate in presence of (S)-4-{3'-Cyano-4'-[3-(3-{2-[5-((3aR,6S,6aS)-2-oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoylamino]-ethyldisulfanyl}-propionylamino)-propoxy]-biphenyl-4-yl}-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulene-6-yl]acetic acid ethyl ester/avidin-resin by pull down assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: Jurkat

Target:  Bromodomain-containing protein 4(ALA1163125)

Document:  ALA3769406

Competitive inhibition of BRD4 in PMA /ionomycin activated human Jurkat cell lysate in presence of (S)-4-{3'-Cyano-4'-[3-(3-{2-[5-((3aR,6S,6aS)-2-oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoylamino]-ethyldisulfanyl}-propionylamino)-propoxy]-biphenyl-4-yl}-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulene-6-yl]acetic acid ethyl ester/avidin-resin by pull down assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
481.585.255.25
481.585.255.25