Basic Information
ID: ALA3774136
Type: ADME
Description: Inhibition of histamine H1 receptor (unknown origin) assessed as inhibition of histamine-induced beta-arrestin internalization preincubated at 10 nM for 3 hrs followed by addition of 0.25 uM histamine measured after 2 hrs by PathHunter cell based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3774136
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 300.83 | 3.68 | 3.68 |
| 321.25 | 3.99 | 3.99 |
| 300.83 | 3.68 | 3.68 |
| 286.81 | 3.33 | 3.33 |
| 314.86 | 4.07 | 4.07 |
| 373.93 | 3.02 | 3.02 |
| 506.09 | 3.07 | 3.07 |
| 335.28 | 4.33 | 4.33 |
| 349.31 | 4.72 | 4.72 |
| 409.36 | 3.71 | 3.71 |