Basic Information
ID: ALA3776167
Type: Binding
Description: Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometry
Format: BAO_0000219
Organism: Homo sapiens
Cell type: NIH3T3
Target: P-glycoprotein 1(ALA4302)
Document: ALA3774328
Inhibition of human MDR1 expressed in mouse NIH/3T3 cells assessed as inhibition of daunomycin efflux incubated for 30 mins by flow cytometry: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3776167
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 578.66 | 3.86 | 3.86 |
| 620.70 | 4.43 | 4.43 |
| 620.70 | 4.43 | 4.43 |
| 655.14 | 4.65 | 4.65 |
| 699.59 | 4.80 | 4.80 |
| 634.72 | 4.82 | 4.82 |
| 648.75 | 5.21 | 5.21 |
| 662.78 | 5.46 | 5.46 |
| 646.73 | 4.82 | 4.82 |
| 682.77 | 5.72 | 5.72 |
| 683.75 | 5.12 | 5.12 |
| 684.74 | 4.51 | 4.51 |
| 649.74 | 4.56 | 4.56 |
| 656.75 | 3.84 | 3.84 |
| 560.64 | 4.90 | 4.90 |
| 662.73 | 5.00 | 5.00 |
| 682.77 | 5.72 | 5.72 |
| 684.74 | 4.51 | 4.51 |
| 692.76 | 4.36 | 4.36 |
| 706.78 | 4.75 | 4.75 |
| 885.06 | 7.39 | 7.39 |
| 776.88 | 5.04 | 5.04 |
| 706.78 | 4.75 | 4.75 |
| 733.86 | 5.23 | 5.23 |
| 747.84 | 4.31 | 4.31 |
| 576.64 | 4.07 | 4.07 |
| 615.55 | 6.35 | 6.35 |
| 580.67 | 3.78 | 3.78 |
| 564.68 | 4.66 | 4.66 |
| 722.78 | 3.72 | 3.72 |