Basic Information
ID: ALA3776326
Type: Binding
Description: Inhibition of N-terminal His6-tagged KDM4C (1 to 352 residues) (unknown origin) expressed in Escherichia coli Rosetta 2(DE3)pLysS using biotinylated histone H3 (1 to 21 residues) lysine 9 trimethylated peptide/50 uM alpha-ketoglutarate as substrate/cofactor measured after 45 mins by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3776326
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 230.22 | 1.73 | 1.73 |
| 244.25 | 2.04 | 2.04 |
| 228.25 | 2.41 | 2.41 |
| 350.33 | 3.11 | 3.11 |
| 350.33 | 3.11 | 3.11 |
| 350.33 | 3.11 | 3.11 |
| 339.31 | 2.70 | 2.70 |
| 348.36 | 3.33 | 3.33 |
| 427.25 | 4.10 | 4.10 |
| 378.38 | 3.34 | 3.34 |
| 378.38 | 3.34 | 3.34 |
| 325.28 | 2.39 | 2.39 |
| 302.29 | 1.74 | 1.74 |
| 240.22 | 2.02 | 2.02 |
| 272.26 | 2.11 | 2.11 |