Basic Information
ID: ALA3776335
Type: Binding
Description: Inhibition of KDM6B (unknown origin) expressed in Escherichia coli using H3 (21 to 44 residues) K27Me3-GGK-Biotin JMJD3 Cognate Ligand/10 uM alpha-ketoglutarate as substrate/cofactor preincubated for 5 mins followed by substrate addition measured after 5 mins by alphascreen assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3776335
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 167.12 | 0.48 | 0.48 |
| 350.33 | 3.11 | 3.11 |
| 339.31 | 2.70 | 2.70 |
| 378.38 | 3.34 | 3.34 |
| 302.29 | 1.74 | 1.74 |
| 272.26 | 2.11 | 2.11 |