Basic Information
ID: ALA3778163
Type: Binding
Description: Inhibition of human KDM6B catalytic domain using H3(20 to 36 residues)K27Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectrometric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3778163
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 138.13 | 0.36 | 0.36 |
| 284.31 | 2.74 | 2.74 |
| 270.29 | 2.35 | 2.35 |
| 256.26 | 1.96 | 1.96 |
| 242.23 | 2.03 | 2.03 |
| 228.25 | 2.39 | 2.39 |
| 242.28 | 2.43 | 2.43 |
| 256.30 | 2.82 | 2.82 |
| 270.33 | 3.21 | 3.21 |
| 180.21 | 1.60 | 1.60 |
| 194.23 | 1.99 | 1.99 |
| 194.23 | 1.85 | 1.85 |
| 181.19 | 0.15 | 0.15 |
| 195.22 | 0.54 | 0.54 |
| 218.21 | 1.98 | 1.98 |
| 248.31 | 2.76 | 2.76 |
| 218.21 | 1.98 | 1.98 |
| 248.31 | 2.76 | 2.76 |