Basic Information
ID: ALA3778166
Type: Binding
Description: Inhibition of full length His-MBP-att-EGLN3 (1 to 239 residues) (unknown origin) in Escherichia coli BL21(DE3)pRR692 cells assessed as hydroxylation of the cy-5 labelled C-terminal oxygen dependent domain of substrate Hif2A preincubated for 30 mins followed by substrate addition measured after 40 mins by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3778166
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 138.13 | 0.36 | 0.36 |
| 284.31 | 2.74 | 2.74 |
| 270.29 | 2.35 | 2.35 |
| 256.26 | 1.96 | 1.96 |
| 242.23 | 2.03 | 2.03 |
| 194.23 | 1.99 | 1.99 |
| 181.19 | 0.15 | 0.15 |
| 195.22 | 0.54 | 0.54 |
| 218.21 | 1.98 | 1.98 |
| 248.31 | 2.76 | 2.76 |