Basic Information
ID: ALA3778243
Type: Binding
Description: Inhibition of recombinant human N-terminal His6-tagged DYRK1A catalytic domain expressed in Escherichia coli BL21(DE3) cells using KKISGRLSPIMTEQ-NH2 as substrate incubated for 15 mins in presence of [gamma-32P]ATP
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3778243
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 212.25 | 3.03 | 3.03 |
| 218.21 | 0.88 | 0.88 |
| 217.22 | 1.13 | 1.13 |
| 257.27 | 1.95 | 1.95 |
| 204.22 | 2.03 | 2.03 |
| 218.21 | 1.75 | 1.75 |
| 230.26 | 2.34 | 2.34 |
| 218.25 | 2.42 | 2.42 |
| 218.25 | 2.41 | 2.41 |
| 216.24 | 1.95 | 1.95 |
| 230.26 | 2.34 | 2.34 |
| 231.28 | 2.63 | 2.63 |
| 232.24 | 1.79 | 1.79 |
| 245.30 | 3.02 | 3.02 |
| 235.26 | 2.02 | 2.02 |
| 251.33 | 2.18 | 2.18 |
| 263.34 | 2.11 | 2.11 |
| 278.38 | 2.79 | 2.79 |
| 272.35 | 2.72 | 2.72 |
| 261.33 | 1.64 | 1.64 |