Basic Information
ID: ALA3778805
Type: Binding
Description: Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for 10 mins measured after 20 mins by alphascreen assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3778805
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 281.34 | 3.46 | 3.46 |
| 359.43 | 2.86 | 2.86 |
| 373.46 | 3.25 | 3.25 |
| 373.46 | 3.25 | 3.25 |
| 147.14 | 0.32 | 0.32 |
| 221.24 | 1.49 | 1.49 |
| 220.26 | 0.89 | 0.89 |
| 206.23 | 1.90 | 1.90 |
| 220.25 | 2.21 | 2.21 |
| 325.35 | 3.16 | 3.16 |
| 238.17 | 1.66 | 1.66 |
| 248.21 | 2.07 | 2.07 |
| 245.27 | 1.02 | 1.02 |
| 230.25 | 1.44 | 1.44 |
| 213.20 | 0.71 | 0.71 |
| 227.23 | 0.72 | 0.72 |
| 213.20 | 0.50 | 0.50 |
| 266.30 | 1.61 | 1.61 |
| 256.26 | 1.20 | 1.20 |
| 259.31 | 0.07 | 0.07 |
| 204.23 | 0.38 | 0.38 |
| 244.30 | 1.30 | 1.30 |
| 321.38 | 1.64 | 1.64 |
| 322.37 | 1.04 | 1.04 |
| 257.25 | 0.04 | 0.04 |
| 284.32 | 0.61 | 0.61 |
| 310.36 | 1.14 | 1.14 |
| 324.39 | 1.53 | 1.53 |
| 378.41 | 2.32 | 2.32 |
| 429.31 | 3.49 | 3.49 |
| 438.51 | 1.58 | 1.58 |
| 385.43 | 2.05 | 2.05 |
| 399.46 | 2.44 | 2.44 |
| 448.96 | 3.65 | 3.65 |
| 414.51 | 3.00 | 3.00 |
| 432.50 | 3.14 | 3.14 |
| 482.51 | 4.02 | 4.02 |
| 483.40 | 4.31 | 4.31 |
| 444.54 | 3.01 | 3.01 |
| 458.52 | 2.73 | 2.73 |
| 415.50 | 2.40 | 2.40 |
| 446.52 | 2.26 | 2.26 |
| 434.93 | 3.58 | 3.58 |
| 418.48 | 3.07 | 3.07 |
| 430.51 | 2.93 | 2.93 |
| 478.58 | 2.33 | 2.33 |
| 425.50 | 2.80 | 2.80 |
| 434.93 | 3.58 | 3.58 |
| 400.49 | 2.93 | 2.93 |
| 401.47 | 2.32 | 2.32 |
| 406.52 | 2.99 | 2.99 |
| 469.38 | 4.23 | 4.23 |
| 434.93 | 3.58 | 3.58 |
| 436.47 | 3.20 | 3.20 |
| 436.47 | 3.20 | 3.20 |
| 468.48 | 3.94 | 3.94 |