Basic Information
ID: ALA3778908
Type: Binding
Description: Inhibition of mouse GAT2 expressed in HEK293 cells assessed as [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA/unlabeled GABA addition measured after 10 mins by liquid scintillation counting analysis
Organism: Mus musculus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3778908
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 129.16 | 0.07 | 0.07 |
| 363.50 | 4.77 | 4.77 |
| 363.50 | 5.24 | 5.24 |
| 377.53 | 5.16 | 5.16 |
| 185.27 | 1.49 | 1.49 |
| 181.24 | 0.71 | 0.71 |
| 195.26 | 1.10 | 1.10 |
| 211.30 | 2.04 | 2.04 |