Basic Information
ID: ALA3778909
Type: Binding
Description: Inhibition of mouse GAT2 expressed in HEK293 cells assessed as remaining [3H]GABA uptake at 100 uM preincubated for 25 mins followed by [3H]GABA/unlabeled GABA addition measured after 10 mins by liquid scintillation counting analysis
Format: BAO_0000219
Organism: Mus musculus
Cell type: HEK293
Target: GABA transporter 3(ALA5205)
Document: ALA3774377
Inhibition of mouse GAT2 expressed in HEK293 cells assessed as remaining [3H]GABA uptake at 100 uM preincubated for 25 mins followed by [3H]GABA/unlabeled GABA addition measured after 10 mins by liquid scintillation counting analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3778909
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.47 | 4.80 | 4.80 |
| 363.50 | 4.72 | 4.72 |
| 363.50 | 5.19 | 5.19 |
| 377.53 | 5.11 | 5.11 |
| 335.45 | 4.46 | 4.46 |
| 349.47 | 4.38 | 4.38 |
| 335.45 | 4.46 | 4.46 |
| 349.47 | 4.38 | 4.38 |
| 349.47 | 4.85 | 4.85 |
| 363.50 | 4.77 | 4.77 |
| 349.47 | 4.85 | 4.85 |
| 363.50 | 5.24 | 5.24 |
| 377.53 | 5.16 | 5.16 |
| 347.46 | 4.14 | 4.14 |
| 361.49 | 4.06 | 4.06 |
| 361.49 | 4.53 | 4.53 |
| 375.51 | 4.45 | 4.45 |
| 333.43 | 3.80 | 3.80 |
| 347.46 | 3.72 | 3.72 |
| 347.46 | 4.19 | 4.19 |
| 361.49 | 4.11 | 4.11 |
| 183.25 | 1.26 | 1.26 |