Assay Report Card

Basic Information

ID: ALA3779076

Type: ADME

Description: Ratio of free plasma concentration in mouse xenografted with human SW620 cells harboring APC mutant at 20 mg/kg, po to IC50 for CDK8-mediated STAT1 phosphorylation at serine727 in human SW620 cells harboring APC mutant

Tissue: Plasma

Cell type: SW-620

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
319.372.402.40