Inhibition of human EGFP-tagged SOD1 A4V mRNA mutant induced endoplasmic reticulum stress expressed in mouse Neuro2a cells assessed as reduction in nu...

Basic Information

ID: ALA3779164

Type: Binding

Description: Inhibition of human EGFP-tagged SOD1 A4V mRNA mutant induced endoplasmic reticulum stress expressed in mouse Neuro2a cells assessed as reduction in nuclear CHOP activation at 25 uM measured 72 hrs post transfection by Hoechst33342 staining-based epifluorescence microscopic analysis (Rvb = 35 to 37%)

Format: BAO_0000219

Organism: Homo sapiens

Cell type: Neuro2a

Target:  Superoxide dismutase(ALA2354)

Document:  ALA3774353

Inhibition of human EGFP-tagged SOD1 A4V mRNA mutant induced endoplasmic reticulum stress expressed in mouse Neuro2a cells assessed as reduction in nuclear CHOP activation at 25 uM measured 72 hrs post transfection by Hoechst33342 staining-based epifluorescence microscopic analysis (Rvb = 35 to 37%): 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
2734.66
2877.85
3030.22
2668.65
2436.37
2476.39
262.400.390.39