Basic Information
ID: ALA3779189
Type: Binding
Description: Inhibition of CDK8 (unknown origin) expressed in 7dF3 clone of human HEK293 cells preincubated for 2 hrs followed by addition of beta-estradiol by luciferase assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3779189
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 231.30 | 2.12 | 2.12 |
| 325.37 | 2.53 | 2.53 |
| 279.34 | 2.82 | 2.82 |
| 319.37 | 2.40 | 2.40 |
| 319.37 | 2.40 | 2.40 |
| 345.41 | 2.91 | 2.91 |
| 403.49 | 3.15 | 3.15 |
| 368.44 | 3.95 | 3.95 |
| 368.44 | 3.95 | 3.95 |
| 380.46 | 4.20 | 4.20 |
| 345.41 | 3.51 | 3.51 |
| 381.46 | 2.93 | 2.93 |
| 371.44 | 3.68 | 3.68 |
| 388.48 | 3.10 | 3.10 |
| 373.46 | 3.39 | 3.39 |
| 407.50 | 2.99 | 2.99 |
| 401.47 | 2.76 | 2.76 |
| 401.47 | 2.76 | 2.76 |
| 331.38 | 2.65 | 2.65 |
| 371.44 | 3.45 | 3.45 |
| 407.42 | 3.65 | 3.65 |
| 387.44 | 2.37 | 2.37 |
| 401.47 | 3.03 | 3.03 |
| 385.47 | 3.79 | 3.79 |
| 421.45 | 4.04 | 4.04 |
| 401.47 | 3.03 | 3.03 |
| 400.49 | 2.60 | 2.60 |
| 399.50 | 4.18 | 4.18 |
| 375.43 | 2.25 | 2.25 |
| 395.41 | 3.52 | 3.52 |
| 361.41 | 1.86 | 1.86 |
| 375.43 | 2.51 | 2.51 |