Basic Information
ID: ALA3782657
Type: Binding
Description: Inhibition of human His6-tagged BRD4 bromodomain 1 (N44 to E168 residues) expressed in Escherichia coli BL21(DE3) cells using biotin-H4KAc4 as substrate incubated for 2 hrs by alphascreen assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3782657
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 352.42 | 3.62 | 3.62 |
| 457.00 | 5.53 | 5.53 |
| 389.48 | 1.43 | 1.43 |
| 459.57 | 3.50 | 3.50 |
| 401.49 | 2.11 | 2.11 |
| 415.52 | 2.36 | 2.36 |
| 394.45 | 3.82 | 3.82 |
| 409.47 | 3.58 | 3.58 |
| 431.50 | 2.27 | 2.27 |
| 386.86 | 4.27 | 4.27 |
| 386.86 | 4.27 | 4.27 |
| 386.86 | 4.27 | 4.27 |
| 396.42 | 3.32 | 3.32 |
| 396.42 | 3.32 | 3.32 |
| 396.42 | 3.32 | 3.32 |
| 370.41 | 3.76 | 3.76 |
| 290.34 | 1.73 | 1.73 |
| 304.37 | 2.12 | 2.12 |
| 318.40 | 2.51 | 2.51 |
| 332.43 | 2.90 | 2.90 |
| 332.43 | 2.75 | 2.75 |
| 346.45 | 3.29 | 3.29 |
| 360.48 | 3.68 | 3.68 |
| 447.56 | 3.40 | 3.40 |
| 361.42 | 1.23 | 1.23 |
| 344.44 | 3.04 | 3.04 |
| 358.46 | 3.43 | 3.43 |
| 372.49 | 3.82 | 3.82 |
| 346.41 | 1.89 | 1.89 |
| 345.42 | 1.46 | 1.46 |
| 360.44 | 2.28 | 2.28 |
| 384.43 | 3.44 | 3.44 |
| 401.49 | 2.29 | 2.29 |
| 402.47 | 2.74 | 2.74 |
| 459.57 | 3.50 | 3.50 |
| 445.54 | 3.11 | 3.11 |
| 431.51 | 2.72 | 2.72 |
| 387.46 | 2.65 | 2.65 |
| 388.49 | 2.91 | 2.91 |
| 387.51 | 2.58 | 2.58 |
| 386.52 | 4.07 | 4.07 |
| 416.55 | 1.74 | 1.74 |
| 304.37 | 2.48 | 2.48 |
| 330.41 | 3.02 | 3.02 |
| 318.40 | 2.51 | 2.51 |
| 344.44 | 3.04 | 3.04 |
| 346.45 | 3.29 | 3.29 |
| 372.49 | 3.82 | 3.82 |
| 360.48 | 3.53 | 3.53 |
| 386.52 | 4.07 | 4.07 |
| 304.37 | 2.58 | 2.58 |
| 318.40 | 2.97 | 2.97 |
| 332.43 | 3.36 | 3.36 |
| 344.44 | 3.50 | 3.50 |
| 358.46 | 3.89 | 3.89 |
| 384.43 | 3.90 | 3.90 |
| 384.43 | 3.90 | 3.90 |
| 384.43 | 3.90 | 3.90 |
| 400.89 | 4.42 | 4.42 |
| 380.47 | 4.07 | 4.07 |
| 358.44 | 3.68 | 3.68 |
| 352.42 | 3.62 | 3.62 |
| 370.40 | 3.76 | 3.76 |
| 370.40 | 3.76 | 3.76 |
| 431.31 | 4.38 | 4.38 |
| 404.85 | 4.41 | 4.41 |
| 404.85 | 4.41 | 4.41 |
| 388.39 | 3.90 | 3.90 |
| 421.31 | 4.93 | 4.93 |
| 421.31 | 4.93 | 4.93 |
| 421.31 | 4.93 | 4.93 |
| 366.44 | 3.93 | 3.93 |
| 377.43 | 3.49 | 3.49 |
| 397.41 | 3.53 | 3.53 |
| 410.45 | 3.41 | 3.41 |
| 396.42 | 3.32 | 3.32 |
| 410.45 | 3.41 | 3.41 |
| 396.42 | 3.32 | 3.32 |
| 416.89 | 4.28 | 4.28 |
| 461.34 | 4.39 | 4.39 |
| 412.47 | 3.64 | 3.64 |