Assay Report Card

Basic Information

ID: ALA3782658

Type: Binding

Description: Binding affinity to human His6-tagged BRD4 bromodomain 1 (N44 to E168 residues) expressed in Escherichia coli BL21(DE3) cells at 200 uM incubated for 30 mins by SYPRO orange staining based fluorescence thermal shift assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
352.423.623.62
457.005.535.53
404.452.352.35
389.481.431.43
459.573.503.50
401.492.112.11
415.522.362.36
394.453.823.82
509.055.485.48
386.864.274.27
386.864.274.27
386.864.274.27
396.423.323.32
396.423.323.32
396.423.323.32
370.413.763.76
290.341.731.73
304.372.122.12
318.402.512.51
332.432.902.90
332.432.752.75
346.453.293.29
360.483.683.68
447.563.403.40
361.421.231.23
344.443.043.04
358.463.433.43
372.493.823.82
346.411.891.89
345.421.461.46
360.442.282.28
384.433.443.44
401.492.292.29
402.472.742.74
459.573.503.50
445.543.113.11
431.512.722.72
387.462.652.65
388.492.912.91
387.512.582.58
386.524.074.07
416.551.741.74
304.372.482.48
330.413.023.02
318.402.512.51
344.443.043.04
346.453.293.29
372.493.823.82
360.483.533.53
386.524.074.07
304.372.582.58
318.402.972.97
332.433.363.36
344.443.503.50
358.463.893.89
384.433.903.90
384.433.903.90
384.433.903.90
400.894.424.42
380.474.074.07
358.443.683.68
352.423.623.62
370.403.763.76
370.403.763.76
431.314.384.38
404.854.414.41
404.854.414.41
388.393.903.90
421.314.934.93
421.314.934.93
421.314.934.93
366.443.933.93
377.433.493.49
397.413.533.53
410.453.413.41
396.423.323.32
410.453.413.41
396.423.323.32
416.894.284.28
461.344.394.39
412.473.643.64