Basic Information
ID: ALA3782860
Type: ADME
Description: Drug metabolism in rat liver microsomes assessed as CYP3A4 mediated metabolite M1 formation at 10 uM preincubated for 5 mins followed by addition of NADPH measured after 120 mins by HPLC-TIC chromatography in presence of clomethiazole
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA3782860
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 861.86 | 3.80 | 3.80 |