Assay Report Card

Basic Information

ID: ALA3782867

Type: ADME

Description: Drug metabolism in human liver microsomes assessed as CYP3A4 mediated metabolite M3 formation at 10 uM preincubated for 5 mins followed by addition of NADPH measured after 120 mins by HPLC-TIC chromatography in presence of clomethiazole

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
861.863.803.80