Basic Information
ID: ALA3782872
Type: Binding
Description: Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release preincubated for 15 mins followed by substrate addition measured for 12 mins by fluorescence-based microplate reader analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3782872
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 252.32 | 2.75 | 2.75 |
| 354.84 | 4.01 | 4.01 |
| 437.93 | 4.50 | 4.50 |
| 373.88 | 2.59 | 2.59 |
| 423.39 | 2.51 | 2.51 |
| 373.84 | 2.71 | 2.71 |
| 373.84 | 2.71 | 2.71 |
| 385.94 | 3.56 | 3.56 |
| 523.03 | 4.34 | 4.34 |
| 523.03 | 4.34 | 4.34 |
| 572.54 | 4.25 | 4.25 |
| 521.06 | 5.49 | 5.49 |
| 230.35 | 2.40 | 2.40 |
| 423.39 | 2.51 | 2.51 |