Basic Information
ID: ALA3783190
Type: Functional
Description: Antiinflammatory activity in differentiated human U937 cells assessed as inhibition of LPS-induced of CXCL8 production preincubated for 2 hrs followed by LPS-stimulation for 4 hrs by sandwich ELISA relative to vehicle-treated control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: U-937
Target: NON-PROTEIN TARGET(ALA3879801)
Document: ALA3779765
Antiinflammatory activity in differentiated human U937 cells assessed as inhibition of LPS-induced of CXCL8 production preincubated for 2 hrs followed by LPS-stimulation for 4 hrs by sandwich ELISA relative to vehicle-treated control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3783190
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 527.67 | 5.99 | 5.99 |
| 508.63 | 6.55 | 6.55 |
| 519.65 | 7.29 | 7.29 |
| 519.65 | 7.29 | 7.29 |
| 592.70 | 6.83 | 6.83 |
| 519.65 | 7.29 | 7.29 |
| 534.66 | 6.87 | 6.87 |
| 534.66 | 6.87 | 6.87 |
| 576.70 | 7.25 | 7.25 |
| 576.70 | 7.25 | 7.25 |
| 606.73 | 6.88 | 6.88 |
| 606.73 | 6.88 | 6.88 |
| 576.70 | 6.65 | 6.65 |
| 620.75 | 6.67 | 6.67 |
| 565.68 | 6.51 | 6.51 |
| 606.73 | 6.63 | 6.63 |
| 661.81 | 6.31 | 6.31 |
| 592.70 | 7.47 | 7.47 |
| 598.73 | 6.62 | 6.62 |
| 562.67 | 7.21 | 7.21 |
| 591.72 | 7.04 | 7.04 |
| 624.75 | 8.50 | 8.50 |
| 638.77 | 8.43 | 8.43 |
| 605.74 | 6.75 | 6.75 |
| 647.78 | 6.52 | 6.52 |
| 608.77 | 7.55 | 7.55 |
| 640.77 | 6.23 | 6.23 |
| 606.73 | 6.86 | 6.86 |
| 606.73 | 7.40 | 7.40 |
| 620.75 | 7.57 | 7.57 |