Basic Information
ID: ALA3783531
Type: Binding
Description: Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 assessed as 5-LO product formation preincubated for 15 mins followed by addition of arachidonic acid as substrate measured after 10 mins by RP-HPLC analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3783531
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 236.30 | 2.73 | 2.73 |
| 405.88 | 6.56 | 6.56 |
| 389.88 | 6.86 | 6.86 |
| 419.91 | 6.87 | 6.87 |
| 447.92 | 6.73 | 6.73 |
| 451.88 | 6.56 | 6.56 |
| 447.92 | 6.73 | 6.73 |
| 419.86 | 6.25 | 6.25 |
| 423.83 | 6.08 | 6.08 |
| 419.86 | 6.25 | 6.25 |
| 430.85 | 5.81 | 5.81 |
| 440.28 | 6.59 | 6.59 |
| 473.83 | 6.96 | 6.96 |
| 406.83 | 5.33 | 5.33 |
| 456.89 | 6.49 | 6.49 |
| 462.91 | 6.55 | 6.55 |