Assay Report Card

Basic Information

ID: ALA3783609

Type: Binding

Description: Inhibition of MTH1 in human U2OS cell lysates assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate at 1 pM to 10 uM after 1 hr by PPiLight assay

Organism: Homo sapiens

Cell type: U2OS

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
195.271.791.79
211.260.760.76
269.143.073.07
295.173.613.61