Basic Information
ID: ALA3788053
Type: Functional
Description: Negative allosteric modulation of rat mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate induced calcium mobilization by calcium mobilization assay
Organism: Rattus norvegicus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3788053
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 253.31 | 2.49 | 2.49 |
| 253.31 | 2.49 | 2.49 |
| 269.35 | 3.12 | 3.12 |
| 269.35 | 3.12 | 3.12 |
| 295.39 | 3.66 | 3.66 |
| 295.39 | 3.66 | 3.66 |
| 269.35 | 3.13 | 3.13 |
| 255.32 | 2.88 | 2.88 |
| 267.34 | 3.02 | 3.02 |
| 281.36 | 3.41 | 3.41 |
| 295.39 | 3.80 | 3.80 |
| 301.35 | 2.86 | 2.86 |
| 319.41 | 3.51 | 3.51 |
| 319.41 | 3.66 | 3.66 |
| 335.41 | 2.77 | 2.77 |
| 303.32 | 3.27 | 3.27 |
| 281.36 | 3.27 | 3.27 |
| 295.39 | 3.66 | 3.66 |
| 279.35 | 2.88 | 2.88 |
| 321.43 | 3.76 | 3.76 |
| 321.43 | 3.76 | 3.76 |
| 321.43 | 3.90 | 3.90 |
| 295.39 | 3.58 | 3.58 |
| 335.46 | 4.07 | 4.07 |
| 335.46 | 4.21 | 4.21 |
| 334.43 | 3.10 | 3.10 |
| 296.38 | 2.85 | 2.85 |
| 310.41 | 3.31 | 3.31 |
| 324.43 | 3.33 | 3.33 |
| 338.46 | 4.09 | 4.09 |
| 354.46 | 3.33 | 3.33 |