Basic Information
ID: ALA3788097
Type: Binding
Description: Agonist activity at human alpha7 nAChR expressed in xenopus oocytes preincubated for 10 mins followed by acetylcholine addition by patch clamp electrophysiological assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Neuronal acetylcholine receptor protein alpha-7 subunit(ALA2492)
Document: ALA3785087
Agonist activity at human alpha7 nAChR expressed in xenopus oocytes preincubated for 10 mins followed by acetylcholine addition by patch clamp electrophysiological assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3788097
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 320.85 | 3.38 | 3.38 |
| 388.52 | 3.50 | 3.50 |
| 481.98 | 3.17 | 3.17 |
| 481.98 | 3.17 | 3.17 |
| 481.98 | 3.17 | 3.17 |
| 516.43 | 3.82 | 3.82 |
| 550.87 | 4.48 | 4.48 |
| 499.97 | 3.31 | 3.31 |
| 499.97 | 3.31 | 3.31 |
| 549.98 | 4.19 | 4.19 |
| 526.98 | 3.08 | 3.08 |
| 497.98 | 2.88 | 2.88 |
| 409.92 | 2.99 | 2.99 |
| 444.36 | 3.65 | 3.65 |
| 444.36 | 3.65 | 3.65 |
| 488.81 | 3.76 | 3.76 |
| 488.81 | 3.76 | 3.76 |
| 427.91 | 3.13 | 3.13 |
| 486.02 | 4.66 | 4.66 |
| 459.98 | 4.15 | 4.15 |
| 302.35 | 1.61 | 1.61 |
| 363.26 | 2.23 | 2.23 |
| 270.34 | 1.16 | 1.16 |
| 269.35 | 1.76 | 1.76 |
| 303.79 | 2.42 | 2.42 |
| 348.24 | 2.53 | 2.53 |
| 283.38 | 2.07 | 2.07 |
| 303.79 | 2.42 | 2.42 |
| 348.24 | 2.53 | 2.53 |
| 303.79 | 2.42 | 2.42 |
| 348.24 | 2.53 | 2.53 |
| 303.79 | 2.42 | 2.42 |
| 348.24 | 2.53 | 2.53 |
| 287.34 | 1.90 | 1.90 |
| 345.45 | 3.43 | 3.43 |
| 345.45 | 3.43 | 3.43 |
| 345.45 | 3.43 | 3.43 |
| 345.45 | 3.43 | 3.43 |
| 359.47 | 3.74 | 3.74 |
| 359.47 | 3.74 | 3.74 |
| 359.47 | 3.74 | 3.74 |
| 359.47 | 3.74 | 3.74 |
| 351.48 | 3.49 | 3.49 |
| 421.54 | 5.10 | 5.10 |
| 351.48 | 3.49 | 3.49 |
| 351.48 | 3.49 | 3.49 |
| 401.55 | 4.73 | 4.73 |
| 401.55 | 4.73 | 4.73 |