Basic Information
ID: ALA3788342
Type: Binding
Description: Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid as substrate measured after 2 mins by enzyme immunoassay
Format: BAO_0000357
Organism: Ovis aries
Target: Cyclooxygenase-2(ALA4102)
Document: ALA3785088
Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid as substrate measured after 2 mins by enzyme immunoassay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3788342
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.38 | 3.51 | 3.51 |
| 415.45 | 3.13 | 3.13 |
| 417.44 | 2.94 | 2.94 |
| 429.48 | 2.81 | 2.81 |
| 403.41 | 3.26 | 3.26 |
| 464.50 | 1.77 | 1.77 |
| 478.53 | 1.45 | 1.45 |
| 489.53 | 2.82 | 2.82 |
| 417.44 | 3.65 | 3.65 |
| 429.48 | 3.52 | 3.52 |
| 478.53 | 2.16 | 2.16 |
| 431.47 | 3.33 | 3.33 |
| 443.50 | 3.20 | 3.20 |
| 388.40 | 3.50 | 3.50 |
| 400.43 | 3.37 | 3.37 |