Basic Information
ID: ALA3788464
Type: Binding
Description: Pharmacological chaperone activity at beta-glucocerebrosidase N370S mutant in Gaucher disease patient-derived lymphoblasts with GCase N370S mutant assessed as increase in enzyme activity at 2.5 uM after 3 days by fluorimetric analysis relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: Beta-glucocerebrosidase(ALA2179)
Document: ALA3784998
Pharmacological chaperone activity at beta-glucocerebrosidase N370S mutant in Gaucher disease patient-derived lymphoblasts with GCase N370S mutant assessed as increase in enzyme activity at 2.5 uM after 3 days by fluorimetric analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3788464
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 147.17 | -2.08 | -2.08 |
| 289.42 | 0.50 | 0.50 |