Basic Information
ID: ALA3788474
Type: Binding
Description: Pharmacological chaperone activity at beta-glucocerebrosidase N370S mutant in Gaucher disease patient-derived lymphoblasts with GCase N370S mutant assessed as increase in enzyme activity at 3.125 to 100 uM after 3 days by fluorimetric analysis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3788474
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 147.17 | -2.08 | -2.08 |
| 289.42 | 0.50 | 0.50 |
| 192.17 | -3.18 | -3.18 |
| 311.29 | -1.40 | -1.40 |
| 361.35 | -0.25 | -0.25 |
| 403.39 | 0.39 | 0.39 |
| 347.27 | -1.13 | -1.13 |
| 413.74 | 0.27 | 0.27 |
| 357.39 | -0.68 | -0.68 |
| 317.32 | -1.34 | -1.34 |
| 369.36 | -1.40 | -1.40 |
| 369.42 | -0.96 | -0.96 |
| 291.30 | -2.13 | -2.13 |
| 403.52 | 0.99 | 0.99 |