Basic Information
ID: ALA3788794
Type: Binding
Description: Inhibition of HCV genotype 1b NS3/4A protease D168Y mutant using Ac-C(Eu)DDMEEAbu[COO]ASK(QSY7)-amide as substrate preincubated for 30 mins followed by substrate addition measured after 2.5 hrs by TRF assay
Organism: Hepatitis C virus subtype 1b
Activity Charts
Bioactivity
Activity Types for Assay ALA3788794
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 766.92 | 3.30 | 3.30 |
| 697.86 | 3.58 | 3.58 |
| 737.92 | 4.21 | 4.21 |
| 749.93 | 4.49 | 4.49 |
| 833.93 | 5.07 | 5.07 |