Assay Report Card

Basic Information

ID: ALA3789256

Type: Binding

Description: Inhibition of CYP26A1-mediated atRA metabolism in human HepG2 cells assessed as atRA level in cell media at 1 uM after 24 hrs in presence of 100 nM atRA by LC/MS-MS analysis (Rvb = 13.2 +/- 0.14 nM)

Organism: Homo sapiens

Cell type: HepG2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
406.525.385.38
408.545.305.30
440.676.736.73