Basic Information
ID: ALA3789261
Type: ADME
Description: Inhibition of CYP3A4 in human liver microsomes at 10 uM using midazolam as substrate by LC-MS/MS analysis in presence of NADPH
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA3789261
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 406.52 | 5.38 | 5.38 |
| 408.54 | 5.30 | 5.30 |
| 440.67 | 6.73 | 6.73 |