Basic Information
ID: ALA3789263
Type: Binding
Description: Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addition measured after 5 mins by HPLC analysis in presence of rat P450 reductase
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA3789263
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.49 | 6.10 | 6.10 |
| 386.49 | 6.12 | 6.12 |
| 362.47 | 5.36 | 5.36 |
| 336.43 | 4.96 | 4.96 |
| 412.62 | 6.41 | 6.41 |
| 380.48 | 4.98 | 4.98 |
| 308.77 | 4.05 | 4.05 |
| 377.52 | 5.66 | 5.66 |
| 430.54 | 6.13 | 6.13 |
| 462.68 | 7.57 | 7.57 |
| 366.46 | 5.00 | 5.00 |
| 368.47 | 4.85 | 4.85 |
| 381.47 | 4.99 | 4.99 |
| 350.50 | 5.64 | 5.64 |
| 406.52 | 5.38 | 5.38 |
| 408.54 | 5.30 | 5.30 |
| 364.49 | 5.28 | 5.28 |
| 438.66 | 6.81 | 6.81 |
| 440.67 | 6.73 | 6.73 |
| 400.54 | 4.89 | 4.89 |
| 354.52 | 5.81 | 5.81 |
| 354.52 | 5.81 | 5.81 |
| 386.51 | 4.50 | 4.50 |
| 386.51 | 4.50 | 4.50 |