Basic Information
ID: ALA3789540
Type: Binding
Description: Inhibition of human DHFR assessed as conversion of dihydrofolic acid to tetrahydrfolic acid by enzyme immunoassay in presence of NADPH
Format: BAO_0000357
Organism: Homo sapiens
Target: Dihydrofolate reductase(ALA202)
Document: ALA3785084
Inhibition of human DHFR assessed as conversion of dihydrofolic acid to tetrahydrfolic acid by enzyme immunoassay in presence of NADPH: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3789540
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.45 | 0.27 | 0.27 |
| 297.31 | 2.90 | 2.90 |
| 576.66 | 6.64 | 6.64 |
| 666.65 | 6.46 | 6.46 |
| 606.69 | 5.81 | 5.81 |
| 866.63 | 12.71 | 12.71 |
| 566.53 | 1.16 | 1.16 |
| 598.67 | 1.49 | 1.49 |
| 622.64 | 2.52 | 2.52 |
| 727.65 | 8.58 | 8.58 |