Basic Information
ID: ALA3789591
Type: Binding
Description: Antagonist activity at rat TRPA1 expressed in tetracycline-inducible T-REx expression system transfected CHO cells assessed as inhibition of AITC-induced Ca2+ influx preincubated for 2 mins followed by AITC addition measured for 2 mins by Fluo-4 dye based FLIPR assay
Organism: Rattus norvegicus
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA3789591
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 321.38 | 2.06 | 2.06 |
| 387.39 | 2.67 | 2.67 |
| 351.41 | 2.07 | 2.07 |
| 351.41 | 2.07 | 2.07 |
| 351.41 | 2.07 | 2.07 |
| 355.83 | 2.72 | 2.72 |
| 341.80 | 2.41 | 2.41 |
| 355.83 | 2.72 | 2.72 |
| 355.83 | 2.72 | 2.72 |
| 355.83 | 2.72 | 2.72 |
| 409.80 | 3.43 | 3.43 |
| 359.79 | 2.55 | 2.55 |
| 371.82 | 2.42 | 2.42 |
| 366.81 | 2.28 | 2.28 |
| 342.79 | 1.80 | 1.80 |
| 342.79 | 1.80 | 1.80 |
| 367.80 | 2.66 | 2.66 |
| 367.80 | 2.66 | 2.66 |
| 367.80 | 2.66 | 2.66 |
| 368.78 | 2.06 | 2.06 |
| 368.78 | 2.06 | 2.06 |
| 368.78 | 2.06 | 2.06 |
| 381.82 | 2.97 | 2.97 |
| 370.80 | 2.00 | 2.00 |
| 370.80 | 2.00 | 2.00 |
| 370.80 | 2.00 | 2.00 |
| 368.78 | 2.06 | 2.06 |
| 383.80 | 2.15 | 2.15 |
| 385.79 | 3.13 | 3.13 |
| 381.82 | 3.22 | 3.22 |
| 365.78 | 3.05 | 3.05 |
| 379.81 | 3.44 | 3.44 |
| 382.81 | 2.78 | 2.78 |
| 382.81 | 2.78 | 2.78 |