Basic Information
ID: ALA3789902
Type: Functional
Description: Positive allosteric modulatory activity at human mGlu1 receptor expressed in wild type T-Rex293 cells assessed as increase in glutamate-induced calcium mobilization pre-incubated for 2.5 mins before glutamate stimulation for 1 min relative to glutamate alone
Organism: Homo sapiens
Cell type: T-Rex293
Activity Charts
Bioactivity
Activity Types for Assay ALA3789902
%max
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 398.78 | 4.43 | 4.43 |
| 364.33 | 3.78 | 3.78 |
| 378.36 | 4.09 | 4.09 |
| 398.80 | 4.44 | 4.44 |
| 366.80 | 4.65 | 4.65 |
| 352.82 | 5.01 | 5.01 |
| 352.82 | 5.19 | 5.19 |
| 353.81 | 4.41 | 4.41 |
| 368.82 | 5.02 | 5.02 |
| 369.81 | 4.42 | 4.42 |
| 380.83 | 4.70 | 4.70 |
| 366.85 | 5.06 | 5.06 |
| 401.25 | 5.31 | 5.31 |
| 401.25 | 5.31 | 5.31 |
| 401.25 | 5.31 | 5.31 |
| 380.83 | 4.96 | 4.96 |
| 384.79 | 4.79 | 4.79 |
| 445.70 | 5.42 | 5.42 |
| 434.80 | 5.67 | 5.67 |
| 391.81 | 4.53 | 4.53 |
| 394.86 | 5.39 | 5.39 |
| 332.36 | 4.00 | 4.00 |
| 366.80 | 4.65 | 4.65 |
| 366.80 | 4.65 | 4.65 |
| 435.69 | 5.96 | 5.96 |
| 384.79 | 4.79 | 4.79 |
| 412.28 | 5.11 | 5.11 |
| 412.28 | 5.11 | 5.11 |
| 432.69 | 5.45 | 5.45 |
| 432.69 | 5.45 | 5.45 |
| 383.86 | 4.52 | 4.52 |
| 418.31 | 5.17 | 5.17 |
| 418.31 | 5.17 | 5.17 |
| 394.81 | 4.22 | 4.22 |
| 408.84 | 4.15 | 4.15 |
| 380.83 | 5.10 | 5.10 |