Basic Information
ID: ALA3790124
Type: Binding
Description: Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting method
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA3790124
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 436.41 | -0.20 | -0.20 |
| 413.90 | 3.37 | 3.37 |
| 443.93 | 2.74 | 2.74 |
| 535.04 | 3.91 | 3.91 |
| 563.10 | 4.69 | 4.69 |
| 539.03 | 3.43 | 3.43 |
| 553.02 | 2.82 | 2.82 |
| 538.99 | 2.73 | 2.73 |
| 442.94 | 2.70 | 2.70 |
| 484.98 | 2.88 | 2.88 |
| 519.43 | 3.10 | 3.10 |
| 553.87 | 3.66 | 3.66 |
| 533.45 | 3.49 | 3.49 |
| 577.90 | 3.64 | 3.64 |
| 513.03 | 3.52 | 3.52 |
| 511.02 | 3.27 | 3.27 |
| 577.08 | 4.18 | 4.18 |
| 595.52 | 4.91 | 4.91 |
| 538.00 | 3.16 | 3.16 |
| 567.11 | 4.16 | 4.16 |
| 593.15 | 4.65 | 4.65 |
| 528.99 | 2.03 | 2.03 |
| 543.02 | 2.42 | 2.42 |
| 543.02 | 2.42 | 2.42 |
| 557.04 | 2.81 | 2.81 |
| 571.07 | 3.20 | 3.20 |
| 528.99 | 2.33 | 2.33 |
| 548.47 | 3.28 | 3.28 |
| 562.49 | 3.67 | 3.67 |
| 572.06 | 2.61 | 2.61 |
| 558.03 | 3.20 | 3.20 |
| 516.06 | 2.84 | 2.84 |
| 530.09 | 3.23 | 3.23 |
| 588.13 | 2.77 | 2.77 |
| 574.14 | 3.24 | 3.24 |
| 612.58 | 5.38 | 5.38 |