Assay Report Card

Basic Information

ID: ALA3790451

Type: Binding

Description: Pharmacological chaperone activity at beta-glucocerebrosidase N370S mutant in Gaucher disease patient-derived lymphoblasts with GCase N370S mutant assessed as increase in enzyme activity at 12.5 uM after 3 days by fluorimetric analysis relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
147.17-2.08-2.08
289.420.500.50